Gram Negative Rods (GIT)
Most common features of all the gram -ve rods of the enteric tract ( except
P. aeruginosa )are i.
Fcaultative anaerobes ii.
ferment glucose iii.
oxidase negative iv. reduce nitrates to nitrites.
E. coli ( GIT Module and KUB Module )
- Most common cause of UTI (urinary tract infection).
- major cause of traveler's diarrhea.
- also cause neonatal meningitis
- O157:H7 strain causes bloody diarrhea and hemolytic uremic syndrome.
- Pathogenisis is mostly through enterotoxins
Labs:
- Ferment lactose and form Pink colonies.
- On EMB agar, form green sheen colonies.
- E.coli O157:H7 doesnt ferment sorbitol.
Salmonella
- common cause of typhoid fever (S.typhi).
- causes enterocolitis.
- animal source of salmonella is poultry and eggs.
- S. typhi is transmitted only by humans. ( carrier rate is higher among women)
Labs: ( are important for exam and viva )
- In typhoid fever rose spots may present on abdomens.
- Widal test commonly used for detecting antibodies in patient serum.
- Do not ferment lactose but produce H2S.